Linezolid-associated optic neuropathy in drug-resistant tuberculosis patients in Mumbai, India

Patients on linezolid-containing drug-resistant TB (DR-TB) regimen often develop adverse-events

From:
Foreign, Commonwealth & Development Office
Published
2 November 2017
Country:
India
Document Type:
Research Paper
Theme:
Health
First published:
1 September 2016
Authors:
Mehta, S, Das M., Laxmeshwar, C, Jonckheere, S, Thi, S.S and Isaakidia, P

Abstract

This study was a retrospective cohort study using routine clinical and laboratory data in M茅decins Sans Fronti猫res (MSF) HIV/DR-TB clinic in collaboration with Lilavati Hospital & Research Center, Mumbai, India. All DR-TB patients on linezolid-containing treatment regimens were included in the study and underwent routine evaluations for systemic and/or ocular complaints. Ophthalmological evaluation by a consultant ophthalmologist included visual-acuity screening, slit-lamp examination and dilated fundus examination.

This research was supported by the UK Department for International Development鈥檚 Operational Research Capacity Building Programme led by the International Union Against TB and Lung Disease (The Union)

Citation

Mehta S, Das M, Laxmeshwar C, Jonckheere S, Thi SS, Isaakidis P (2016) LinezolidAssociatedOptic Neuropathy in Drug-Resistant Tuberculosis Patients in Mumbai, India. PLoS ONE 11(9): e0162138.

Updates to this page

Published 2 November 2017
Contents