Cassava haplotype map highlights fixation of deleterious mutations during clonal propagation
A cassava haplotype map through deep sequencing 241 diverse accessions identified more than 28 million segregating variants
Abstract
Cassava is an important staple food crop in Africa and South America; however, ubiquitous deleterious mutations may severely decrease its fitness. To evaluate these deleterious mutations, the authors constructed a cassava haplotype map through deep sequencing 241 diverse accessions and identified more than 28 million segregating variants.
This work is part of the 鈥淣ext Generation Cassava Breeding Project鈥� which is supported by the UK Department for International Development, in partnership with the Bill & Melinda Gates Foundation.
Citation
Ramu, P., W. Esuma, R. Kawuki, I.Y. Rabbi, C. Egesi, J. V Bredeson, R.S. Bart, J. Verma, E.S. Buckler, and F. Lu. Cassava haplotype map highlights fixation of deleterious mutations during clonal propagation. Nature Genetics; https://doi.org/10.1038/ng.3845