Mpox: affected countries
This page provides an overview of mpox epidemiology, indicating where there may be a risk of clade I and clade II mpox exposure.
Global overview
There are 2 major genetic groups (clades) of MPXV, clade I (formerly known as Central African or Congo basin clade) and clade II (formerly known as West African clade). Clade I is split into clade Ia and clade Ib. Clade II is split into clade IIa and clade IIb, and all clades have subgroup clusters called lineages. The majority of the cases seen in the global outbreak which started in 2022 were from clade IIb, lineage B.1. The latest epidemiological data on mpox (all clades) can be found on the World Health Organization (WHO) .
Figure 1. Geographic distribution of MPXV clades, by country, as of 13 March 2025 (adapted from the World Health Organization ). The map is not indicative of ongoing outbreaks and is generated from available laboratory data associated with both travel-associated and locally acquired cases.
Table 1. Countries reporting the highest number of recent mpox cases (all clades). Adapted from , updated 25 March 2025. Data as of 28 February 2025
| Country | Cases in the past month | Total confirmed cases | Clades reported |
|---|---|---|---|
| Uganda | 1,327 | 3,769 | Clade Ib |
| Democratic Republic of the Congo | 1,107 | 18,949 | Clades Ia and Ib |
| Burundi | 259 | 3,547 | Clade Ib |
| Spain | 71 | 8,585 | Clade II |
| Nigeria | 54 | 1,122 | Clade II |
| Brazil | 52 | 13,718 | Clades Ib (travel-associated only) and II |
| Australia | 40 | 1,684 | Clade II |
| Mexico | 23 | 4,230 | Clade II |
| Philippines | 22 | 108 | Clade II |
| United States of America | 22 | 34,651 | Clades Ib (travel-associated only) and II |
Clade I mpox outbreak: 2024 to 2025
On 14 August 2024, the WHO declared a Public Health Emergency of International Concern in response to the upsurge of clade I mpox in the Democratic Republic of the Congo and a growing number of countries in the African Region. This outbreak remains ongoing, with evidence of sustained community transmission in several countries, as per Table 2.
Travel-associated clade I mpox cases outside the African Region have been reported in several countries. Whilst there is currently no evidence of sustained community transmission of clade I mpox outside of African Region countries, limited local transmission (for example, household transmission) has been reported in , , , and the United Kingdom.
Figure 2. African region countries reporting laboratory confirmed clade I mpox (historic or current)
Mpox of an unknown clade has been reported in Gabon but is presumed to be clade I (due to case travel history).
Table 2. Countries with evidence of ongoing clade I mpox transmission or exportation during the 2024 to 2025 outbreak
| Country | Evidence of transmission | Clade |
|---|---|---|
| Burundi | Community transmission | Ib |
| Central African Republic | Community transmission | Ia |
| Democratic Republic of the Congo | Community transmission | Ia and Ib |
| Gabon | Community transmission | I |
| Kenya | Community transmission | Ib |
| Republic of the Congo | Community transmission | Ia and Ib |
| Rwanda | Community transmission | Ib |
| South Sudan | Unclear (historical community transmission) | Ib (and historical transmission of Ia) |
| Tanzania | Unclear (evidence of exported cases) | Ib |
| Uganda | Community transmission | Ib |
| United Arab Emirates | Unclear (evidence of exported cases) | Ib |
| Zambia | Community transmission | Ib |
Updates to this page
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Updated Table 1 and Africa map.
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Updated to include clade II mpox and world map of mpox clade distribution.
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Added entries for Brazil and Qatar.
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Updated to reflect new cases since 14 February.
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Updated Zambia status.
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Added Republic of Ireland and a few other minor changes.
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Updated the list of affected countries.
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Tanzania added to Table 1. Updates added for travel-associated cases in Germany (URL also updated) and the UK.
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Belgium has been updated to reflect one new case reported in a household contact of their first imported case.
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Updated to include information for Belgium, China and France.
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Updated information for Gabon and added information for United Arab Emirates.
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Updated links and added Oman & Pakistan to list.
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Updated guidance.
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Updated information for imported clade I mpox cases in countries outside of the African region.
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First published.