2021 annual call topic proposals
Published 20 May 2024
漏 Crown copyright 2024
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This publication is available at /government/publications/uk-nsc-previous-annual-call-submissions/2021-annual-call-topic-proposals
罢丑别听UK NSC聽received 4 proposals in 2021:
1. Metachromatic leukodystrophy (MLD)
UK NSC decision: commission more work and add MLD to list of conditions the committee regularly reviews
罢丑别听UK NSC聽received a proposal for the introduction of newborn screening for聽MLD聽and the evaluation group agreed it fell within the聽UK NSC听谤别尘颈迟.
An evidence map was commissioned and its findings were promising. The evidence map recommended further work:
- to evaluate all available screening strategies
- to look in more depth at evidence related to the benefits and/or harms of treatments in presymptomatic patients with聽MLD
- on the question of cost-effectiveness
Chair鈥檚 action was taken to prevent delay to this further work and聽MLD聽will be added to the聽聽kept under regular review.
2. Anorectal malformations
UK NSC decision: evidence map commissioned, no further work
罢丑别听UK NSC聽received a proposal to add anorectal malformations (ARMs) to the newborn and infant physical examination screening programme.
The evaluation group agreed that the topic fell within the remit of the聽UK NSC聽and an evidence map was commissioned.
The evidence map found no suitable studies that reported a screening test used to triage consecutive or randomly selected populations of all newborns and/or infants for聽ARMs.
Both the fetal, maternal and child health (FMCH) group and the聽UK NSC聽noted the findings of the evidence map for聽ARMs聽and agreed no further work should be commissioned at this time.
3. Neonatal diabetes
UK NSC decision: evidence map commissioned, no further work
罢丑别听UK NSC聽received a proposal to screen for neonatal diabetes (NDM) in newborns.
The evaluation group agreed that the topic fell within the remit of the聽UK NSC聽and an evidence map was commissioned.
The evidence map concluded that the volume and type of evidence related to screening for NDM was insufficient to justify an evidence summary and no further work on screening for NDM should be commissioned at this time.
4. Craniosynostosis
UK NSC decision: evidence map commissioned, no further work
罢丑别听UK NSC聽received a proposal to screen for craniosynostosis as part of the Newborn and Infant Physical Examination (NIPE) population screening programme.
The evaluation group agreed that the topic fell within the remit of the聽UK NSC聽and an evidence map was commissioned.
The evidence map concluded that the volume and type of evidence related to screening for craniosynostosis was insufficient to justify an evidence summary and no further work on screening for craniosynostosis should be commissioned at this time.