FOI release

Freedom of Information request on dental anaesthesia (FOI 21/1010)

Published 17 January 2022

漏 Crown copyright 2022

This publication is licensed under the terms of the Open Government Licence v3.0 except where otherwise stated. To view this licence, visit or write to the Information Policy Team, The National Archives, Kew, London TW9 4DU, or email: [email protected].

Where we have identified any third party copyright information you will need to obtain permission from the copyright holders concerned.

This publication is available at /government/publications/freedom-of-information-responses-from-the-mhra-week-commencing-13-september-2021/freedom-of-information-request-on-dental-anaesthesia-foi-211010

14th September 2021

FOI 21/1010

Dear

Thank you for your email.

We have had one defective medicine alert relevant to dental anaesthesia which can be found at the following link:

/drug-device-alerts/all-batches-of-marcain-polyamp-steripack-0-5-bupivacaine-hydrochloride-error-on-carton-and-ampoule-label-about-administration

Also on our website are past editions of Drug Safety Update, our monthly bulletin about medicines safety published on Gov.UK since 2014.

/drug-safety-update

In 2020 we published an article on changes to the availability of topical lidocaine medicines for teething in infants.

/drug-safety-update/oral-lidocaine-containing-products-for-infant-teething-only-to-be-available-under-the-supervision-of-a-pharmacist

In 2014 we published an article on blood concentration limits for certain controlled drugs (including ketamine as a medicine) and driving.

/drug-safety-update/drugs-and-driving-blood-concentration-limits-to-be-set-for-certain-controlled-drugs-in-a-new-legal-offence

In 2019 we also published a letter from a licence holder to healthcare professionals about short-term supply arrangements for ketamine (Ketalar) injections.

Our search included safety information for the following medicines with relevant indications:

  • Lidocaine
  • Ropivacaine
  • Bupivacaine (including combinations with adrenaline)
  • Levobupivacaine
  • Ketamine
  • Esketamine

Please note that organisations other than the MHRA may have issued relevant safety alerts. Many different kinds of alerts can be found on the Central Alerting System

Kind regards,

MHRA Customer Service Centre

Back to top